missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Adenylosuccinate lyase Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 15264-1-AP-20UL
This item is not returnable.
View return policy
Description
ADSL (adenylosuccinate lyase), also known as AMPS, ASL or ASASE, is a 484 amino acid protein that is involved in both purine biosynthesis and in the formation of adenosine monophosphate (AMP) from inosine monophosphate. Expressed ubiquitously, ADSL catalyzes two key reactions in AMP biosynthesis, namely the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and the subsequent removal of fumarate from adenylosuccinate to yield AMP. Defects in the gene encoding ADSL are the cause of adenylosuccinase deficiency (ADSL deficiency), an autosomal recessive disorder characterized by epilepsy, growth retardation and muscular wasting. Multiple isoforms of ADSL exist due to alternative splicing events.Specifications
| Adenylosuccinate lyase | |
| Polyclonal | |
| Unconjugated | |
| ADSL | |
| Adenylosuccinase, adenylosuccinate lyase, ADSL, AMPS, ASASE, ASL | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 11564, 158, 315150 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence | |
| 0.22 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P30566, P54822 | |
| ADSL | |
| Adenylosuccinate lyase Fusion Protein Ag7332 | |
| 20 μL | |
| Primary | |
| Human, Rat, Mouse | |
| Antibody | |
| IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction