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Invitrogen™ Human APC13 Synthetic Peptide
Synthetic Peptide
Brand: Invitrogen™ PEP1070
This item is not returnable.
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Description
APC13 Synthetic Peptide, PEP-1070, from Invitrogen.
Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC13 promotes the stable association of APC3/Cdc27 and APC6/Cdc16 with the APC/C.
Specifications
| 25847 | |
| purified | |
| Human APC13 | |
| -20°C | |
| Liquid | |
| Blocking Assay, Control | |
| No | |
| Peptide | |
| RUO - research use only |
| Human | |
| Q9BS18 | |
| 200 μg/mL | |
| Synthetic Peptide | |
| PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 | |
| ANAPC13 | |
| 0.02% sodium azide | |
| 50 μg | |
| PBS |
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