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ATP citrate lyase Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 15421-1-AP-150UL
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Description
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.Specifications
| ATP citrate lyase | |
| Polyclonal | |
| Unconjugated | |
| ACLY | |
| ACL, ACLY, ATP citrate (pro S ) lyase, ATP citrate lyase, ATP citrate synthase, ATPCL, Citrate cleavage enzyme, CLATP | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 104112, 24159, 47 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot | |
| 0.17 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P16638, P53396, Q91V92 | |
| ACLY | |
| ATP citrate lyase Fusion Protein Ag7709 | |
| 150 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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