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COMT Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 14754-1-AP-20UL
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Description
COMT (Catechol-O-methyltransferase) catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.Specifications
COMT | |
Polyclonal | |
Unconjugated | |
COMT | |
catechol O methyltransferase, COMT | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
12846, 1312, 24267 | |
-20°C | |
Liquid |
Immunoprecipitation, Immunofluorescence, Immunocytochemistry, Immunohistochemistry (Paraffin), Flow Cytometry | |
0.19 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
O88587, P21964, P22734 | |
COMT | |
COMT Fusion Protein Ag6502 | |
20 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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