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COMT Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 14754-1-AP-20UL

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Product Code. 16823564

  • 1081.84 DKK / 20µL

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Description

Description

COMT (Catechol-O-methyltransferase) catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
Specifications

Specifications

COMT
Polyclonal
Unconjugated
COMT
catechol O methyltransferase, COMT
Rabbit
Antigen Affinity Chromatography
RUO
12846, 1312, 24267
-20°C
Liquid
Immunoprecipitation, Immunofluorescence, Immunocytochemistry, Immunohistochemistry (Paraffin), Flow Cytometry
0.19 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O88587, P21964, P22734
COMT
COMT Fusion Protein Ag6502
20 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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