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CRTC2/TORC2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 12497-1-AP-20UL
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Description
CRTC2, also known as TORC2 (Transducers Of Regulated cAMP Response Element-Binding (CREB)) 2 and the related protein CRTC1 are potent CREB coactivators that are exported from the nucleus in a CRM1-dependent manner via phosphorylation-dependent interactions. Studies suggest that their phosphorylation and nuclear/cytoplasmic shuttling play an important role in the regulation of gluconeogenesis by cAMP. CRTC2 is present in both B and T-lymphocytes and abundantly expressed in the thymus. Its activity is important in regulating the expression of genes involved in cellular energy metabolism while CRTC1 is essential for energy balance and fertility.Specifications
| CRTC2/TORC2 | |
| Polyclonal | |
| Unconjugated | |
| CRTC2 | |
| CRTC2, RP11 422P24.6, TORC 2, TORC2, Transducer of CREB protein 2 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 200186, 310615, 74343 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence | |
| 0.45 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q3LRZ1, Q3U182, Q53ET0 | |
| Crtc2 | |
| CRTC2,TORC2 Fusion Protein Ag3167 | |
| 20 μL | |
| Primary | |
| Mouse, Rat, Human | |
| Antibody | |
| IgG |
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