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DOCK3/MOCA Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1081.84 DKK - 3058.99 DKK

Specifications

Antigen DOCK3/MOCA
Concentration 0.49 mg/mL
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16810265
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Proteintech
20683-1-AP-20UL
20 μL
1081.84 DKK
20µL
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16800265
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Proteintech
20683-1-AP-150UL
150 μL
3058.99 DKK
150µL
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Description

Description

Dedicator of cytokinesis3 (DOCK3), also named as MOCA and PBP, is a ∽180 kDa protein involved in signaling transduction. It is a potential guanine nucleotide exchange factor (GEF) which activate some small GTPases by exchanging bound GDP for free GTP. DOCK3 is associated in Alzheimer disease tangles and regulates the accumulation of amyloid precursor protein and beta-amyloid. Overexpression of Dock3 in neural cells promotes axonal outgrowth downstream of brain-derived neurotrophic factor (BDNF) signaling. DOCK3 binds to and inactivates glycogen synthase kinase-3beta (GSK-3beta) at the plasma membrane, thereby promoting axon branching and microtubule assembly. By stimulating actin polymerization and microtubule assembly, DOCK3 plays important roles downstream of BDNF signaling in the CNS.
Specifications

Specifications

DOCK3/MOCA
Western Blot
Unconjugated
Rabbit
Human, Mouse
Q8CIQ7, Q8IZD9
1795, 208869
Peptide
Primary
-20°C
DOCK3
0.49 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
dedicator of cytokinesis 3, DOCK3, KIAA0299, MOCA, Modifier of cell adhesion, PBP, Presenilin binding protein
DOCK3
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

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