Invitrogen™ mirVana™ miRNA Mimic, Negative Control #1

Description

mirVana miRNA Mimic Negative Control No. 1 is a non-targeting control for experiments with mirVana miRNA mimics. Transfected using the same methodology as positive controls and experimental miRNA mimics, it provides a baseline for evaluating effects on target gene expression. Extensively tested in human cell lines and tissues, it ensures no impact on known miRNA functions, making it essential for accurate gene expression studies. Key properties include reliability, superior specificity, and versatile use in vitro and in vivo.

Features of mirVana miRNA Mimic Negative Control include:

• Reliability—maximum and consistent effect in vitro at low concentration and low toxicity
• Superior specificity—the most updated Sanger content with unique Star strand modification
• Versatile use—can be used in vitro and in vivo, offering you consistency throughout your entire research project

What are mirVana miRNA mimics?

mirVana miRNA mimics are small, chemically modified double-stranded RNA molecules designed to mimic endogenous miRNA molecules and enable miRNA functional analysis by up-regulation of miRNA activity. Positive and negative controls are also available for use along with mirVana miRNA mimics in miRNA up-regulation experiments.

Quality control

Each mirVana miRNA Mimic is synthesized and purified in state-of-the-art facilities to meet the highest quality standards. Our rigorous quality control procedures include MALDI-TOF mass spectrometry analysis and analytical HPLC to monitor purity. We also assess each annealed miRNA mimic by gel electrophoresis to ensure proper strand annealing. The result is a premium-quality miRNA mimic that is purified and ready for use.