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  6. Thermo Scientific™ Sodium Deoxycholate Detergent

Thermo Scientific™ Sodium Deoxycholate Detergent

Product Code. 11874141 Shop All Thermo Scientific Products
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Quantity:
5 g
25 g
Unit Size:
25g
5g
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Water-soluble, ionic detergent used in cell lysis buffers (e.g., RIPA buffer) to disrupt protein interactions for liposome and membrane protein isolation.

Thermo Scientific™ Sodium Deoxycholate is an ionic detergent that is especially useful for disrupting and dissociating protein interactions.

Sodium deoxycholate (deoxycholic acid) is a water-soluble, bile-acid, ionic detergent commonly used in protein methods. It is most frequently used as a component of cell lysis buffers (e.g., RIPA buffer) but also has been used for liposome preparation, isolation of membrane proteins and lipids, preventing nonspecific binding in affinity chromatography and a cell culture media supplement.

Highlights:

  • Popular anionic, bile-acid detergent for many laboratory uses
  • Effective in disrupting and dissociating many types of protein interaction
  • Can be removed from solution by dialysis
  • Useful for elution or regeneration of certain kinds of affinity columns
  • High-purity compound with low UV absorptivity

Detergent Properties:

  • Alternative Names: Sodium deoxycholic acid; deoxycholate, sodium salt
  • Chemical Name: 3, 12-α-Dihydroxy-5β-cholan-24-oic acid, monosodium salt
  • Molecular Weight: 414.6
  • Detergent Class: Ionic (anionic)
  • Aggregation Number: 5 (average)
  • Micelle Molecular Weight: 2000 (average)
  • Critical Micelle Concentration (CMC): 2 to 6mM (0.083 to 0.249%, w/v)
  • Cloud Point: Unknown
  • Dialyzable: Yes
TRUSTED_SUSTAINABILITY

Specifications

Product Type Detergent
Content And Storage Store at -20°C
Form Powder
Reagent Type Detergent (Pure)
Quantity 25 g

Safety and Handling

compliance-icons
Product Identifier
  • Sodium Deoxycholate Detergent
 Signal Word
  • Warning
 Hazard Category
  • Acute toxicity Category 4
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H302-Harmful if swallowed.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P264-Wash hands thoroughly after handling.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P310-Immediately call a POISON CENTER/doctor/.
  • P405-Store locked up.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Supplemental information
  • MIXTURE LIST-Contains : sodium 3-droxy-5-oate

For Research Use Only. Not for use in diagnostic procedures.

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