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Invitrogen™ Human FBXL20 Synthetic Peptide

Product Code. 15378760
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Quantity:
50 μg
Unit Size:
50µg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Synthetic Peptide

SCRAPPER Synthetic Peptide, PEP-0606, from Invitrogen.

Members of the F-box protein family, such as Scrapper, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. Scrapper is selectively expressed in the brain, broadly expressed within the mouse CNS and is abundant at presynaptic membrane. Scrapper has orthologs in C. elegans, D. melanogaster, and mammals which suggests that it might function as an important membrane-localized E3 ligase in various species. Scrapper is a major presynaptic E3 ubiquitin ligase that acts through RIM1a via degradation and the ubiquitin-proteasome-system (UPS) pathway to critically regulate synaptic transmission. This identifies protein degradation as a mechanism for holding synaptic communication in check.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 84961
Species Human
Purification Method purified
Accession Number Q96IG2
Common Name Human FBXL20
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol FBXL20
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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