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SHMT2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 11099-1-AP-20UL
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Description
Mammalian serine hydroxymethyltransferase (SHMT) is a tetrameric, pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate in the cytoplasm (cSHMT, SHMT1) and mitochondria (mSHMT, SHMT2). cSHMT preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate, and inhibits SAM synthesis.Specifications
| SHMT2 | |
| Polyclonal | |
| Unconjugated | |
| SHMT2 | |
| GLYA, Serine methylase, SHMT, SHMT2 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 108037, 299857, 6472 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
| 0.2 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| P34897, Q9CZN7 | |
| SHMT2 | |
| SHMT2 Fusion Protein Ag1584 | |
| 20 μL | |
| Primary | |
| Mouse, Human, Rat | |
| Antibody | |
| IgG |
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