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Thermo Scientific Chemicals Thiazolyl Blue tetrazolium bromide, 98%
CAS: 298-93-1 | C18H16BrN5S | 414.33 g/mol
409.41 DKK - 1282.20 DKK
Chemical Identifiers
| CAS | 298-93-1 |
|---|---|
| Molecular Formula | C18H16BrN5S |
| Molecular Weight (g/mol) | 414.33 |
| MDL Number | MFCD00011964,MFCD00066662 |
| InChI Key | AZKSAVLVSZKNRD-UHFFFAOYSA-M |
| Synonym | thiazolyl blue, thiazolyl blue tetrazolium bromide, mmt tetrazolium, methylthiazoletetrazolium, mtt, thiazolyl blue monotetrazolium, thiazole blue, 3-4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide, mtt van, unii-euy85h477i |
| PubChem CID | 64965 |
| ChEBI | CHEBI:53233 |
| IUPAC Name | 2-(3,5-diphenyltetrazol-2-ium-2-yl)-4,5-dimethyl-1,3-thiazole;bromide |
| SMILES | [Br-].CC1=C(C)N=C(S1)[N+]1=NC(=NN1C1=CC=CC=C1)C1=CC=CC=C1 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
11302727
|
Thermo Scientific Chemicals
L11939.03 |
1 g |
409.41 DKK
1g |
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|
11312727
|
Thermo Scientific Chemicals
L11939.06 |
5 g |
1282.20 DKK
5g |
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Description
Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsUsed in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.
Solubility
Soluble in water, ethanol, 2-methoxyethanol and phosphate buffered saline.
Notes
Light, air and moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
Chemical Identifiers
| 298-93-1 | |
| 414.33 | |
| AZKSAVLVSZKNRD-UHFFFAOYSA-M | |
| 64965 | |
| 2-(3,5-diphenyltetrazol-2-ium-2-yl)-4,5-dimethyl-1,3-thiazole;bromide |
| C18H16BrN5S | |
| MFCD00011964,MFCD00066662 | |
| thiazolyl blue, thiazolyl blue tetrazolium bromide, mmt tetrazolium, methylthiazoletetrazolium, mtt, thiazolyl blue monotetrazolium, thiazole blue, 3-4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide, mtt van, unii-euy85h477i | |
| CHEBI:53233 | |
| [Br-].CC1=C(C)N=C(S1)[N+]1=NC(=NN1C1=CC=CC=C1)C1=CC=CC=C1 |
Specifications
| 298-93-1 | |
| Odorless | |
| MFCD00011964,MFCD00066662 | |
| Air, light, and moisture sensitive | |
| Soluble in water,ethanol,2-methoxyethanol and phosphate buffered saline. | |
| [Br-].CC1=C(C)N=C(S1)[N+]1=NC(=NN1C1=CC=CC=C1)C1=CC=CC=C1 | |
| 414.33 | |
| CHEBI:53233 | |
| 98% |
| ∽195°C (decomposition) | |
| C18H16BrN5S | |
| 3825277 | |
| thiazolyl blue, thiazolyl blue tetrazolium bromide, mmt tetrazolium, methylthiazoletetrazolium, mtt, thiazolyl blue monotetrazolium, thiazole blue, 3-4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide, mtt van, unii-euy85h477i | |
| AZKSAVLVSZKNRD-UHFFFAOYSA-M | |
| 2-(3,5-diphenyltetrazol-2-ium-2-yl)-4,5-dimethyl-1,3-thiazole;bromide | |
| 64965 | |
| 414.33 | |
| Thiazolyl Blue tetrazolium bromide |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P201-P202-P261-P264b-P271-P280i-P281-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P362-P501c
H315-H319-H335-H341
missing translation for 'einecsNumber' : 206-069-5
missing translation for 'rtecsNumber' : XF8060000
missing translation for 'tsca' : Yes
Recommended Storage : Ambient temperatures; Store under Nitrogen
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
- Thiazolyl Blue tetrazolium bromide
Signal Word
- Warning
Hazard Category
- Serious eye damage/eye irritation Category 2
- Specific target organ toxicity Category 3
- Skin corrosion/irritation Category 2
Hazard Statement
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
Precautionary Statement
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P405-Store locked up.
- P501-Dispose of contents/container to in accordance with local/regional/national/international regulations..
RUO – Research Use Only
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